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RISK FACTOR'S

  • AGE.

The incidence of breast cancer increases with age. It is not correct to think that from the age of 70 there is no longer any risk.           English

Incidencia de cancer segun edad-2.jpg
  • PREMALIGNANT LESIONS

There is a group of breast lesions that can turn into cancer throughout a woman's life. (Ellis histological classification)

  1. ATYPICAL DUCTAL HYPERPLASIA.

    • DIN 1A: Flat epithelial atypia.

    • DIN 1B:Hyperplasia  atypical

    • DIN 1C: DCIS (low-grade ductal carcinoma in situ).

    • DIN 2: DCIS (ductal carcinoma in situ) intermediate grade.

    • DIN 3: DCIS (ductal carcinoma in situ) high grade.

  2. LOBULAR NEOPLASM.

    • LIN 1. Lobular neoplasm without atypia.

    • LIN 2. Atypical lobular neoplasm.

    • LIN 3.CLIS(Lobular Carcinoma in situ) and the pleomorphic variant CLISP

  3. PAPILLARY LESIONS.

    • adenoma of the nipple

    • intraductal papillomas

    • juvenile papillomatosis

  4. SCLEROSING INJURIES  COMPLEX

  5. COLUMN CELL INJURIES

  6. PSEUDOANGIOMATOUS HYPERPLASIA.

  7. MUCOCELE-LIKE LESIONS

  8. FIBROEPITHELIAL PROLIFERATIONS WITH STROMAL HYPERCELLULARITY

Interesting scientific publication about it: " Premalignant lesions or precursors of breast cancer: diagnostic and therapeutic aspects" Dr.J de Leon Carrillo et al.

These lesions are usually findings found in biopsies performed due to abnormalities detected in mammography and/or casual findings in biopsies of apparently benign tumors.

WOMEN WITH THESE FINDINGS ARE 4 TIMES MORE LIKELY TO HAVE BREAST CANCER THAN THE NORMAL POPULATION.

  • HORMONAL STATES DURING WOMEN'S LIFE .

The influence of women's hormonal states on the incidence and development of  of breast cancer.

It is no accident that the incidence  of breast cancer stands out from the rest of tumors in women over 50 years of age (menopause). Nor is it another coincidence that the growth of breast cancers is much faster in pre-menopausal women than in postmenopausal women.

Late pregnancies (>35 years), late menopause, hormonal contraceptive methods (pill, IUD and subcutaneous hormonal devices), fertilization treatments, and hormone replacement therapy (postmenopause).

 

ALL OF THEM GENERATE HORMONAL STATES THAT SHOULD BE ASSESSED WITH CAUTION AND CONTROLLED   INDIVIDUALIZED

                     !! NEVER BE PART OF THE GENERAL PLANNING!!

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  • FAMILY-GENETIC BACKGROUND .

Contrary to the general idea that exists in the population, only 5 to 10% of cancers have a hereditary origin.

  • TOBACCO, ALCOHOL AND OBESITY.

All of them are also considered external factors that, together with the previous ones, increase the incidence of breast cancer.

  • PREDICTIVE MODEL OF BREAST CANCER

  From Gail (1999) to the present day, statistical models continue to be proposed that can help women to have an assessment of their own risk of suffering from breast cancer .

"According to Dr. Fernando Gomez , in his work the genetic and non-genetic risk factors that predispose to the development of breast cancer are reviewed. The models and strategies most used to objectify these risks are analyzed, among which are mathematical models of breast cancer risk prediction, genetic mutation probability prediction models, and techniques for obtaining epithelial cells from the breast ducts Quantitative risk assessment allows patients to be informed and educated so that they can participate documented and informed decision-making. "

 

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